Archives for September 2022

Top 80 Medical Device Conferences in 2022 – 2023

9 min reading time

Medical Device Conferences 2022 – 2023 is our most comprehensive list of medical device conferences, trade shows, events, and meetings for the medical device industry.
These are the conferences, trade shows, and events the world’s leading professionals attend to do business, learn, and build and solidify relationships.
We at the Medical Devices Group make every effort for the list to be the best and most complete.


If an event is missing, please add it for free:

    1. Liquid Biopsy Surveillance and Early Detection Summit
      November 16-17, 2022 • Boston, MA

      In the wake of new FDA guidance and exciting MRD partnership announcements between Grail and AstraZeneca, Amgen and Bristol Myers Squibb the liquid biopsy industry is experiencing a paradigm shift. Touted as having the potential to transform clinical practice as we know it, technical progress and mounting investment in premetastatic applications are creating huge industry-wide excitement for liquid biopsy-based screening and surveillance for novel precision drug development. With technology maturity on the near horizon, the inaugural Liquid Biopsy Surveillance and Early Detection Summit is your only dedicated platform providing much-needed clarity on the industry’s emerging assays increasingly opening the doors to novel trial design and better patient outcomes.
    2. Symposium on Cell Manufacturing and Commercialization Translating Pluripotent Stem Cell Discoveries to the Clinic
      November 17-19, 2022 • Boston, USA

      The International Society for Stem Cell Research (ISSCR) invites you to join us for the 2022 Symposium on Cell Manufacturing and Commercialization “Translating Pluripotent Stem Cell Discoveries to the Clinic: Preclinical, Manufacturing, and Regulatory Strategies for Success” which will take place at the, Boston Marriott Cambridge Boston, MA from 17-19 November 2022. Registration is open! The meeting will bring together international academic and commercial scientists with expertise in the preclinical, clinical, and regulatory phases to discuss the critical processes and strategies in the successful development of PSC-derived therapies. Sessions will cover some of the latest thinking and approaches for selecting the cell line, characterizing the product and manufacturing considerations, managing the immune system, and working with regulators throughout the process. We hope you can join us in one of the world’s hubs of biotechnology.
    3. Echocardiography Best Practice When To Use Multi-Modality Imaging
      November 17-20, 2022 • Fairmont Scottsdale Princess

      Experts in echocardiography will use illustrative cases and lectures to highlight the role of echocardiography in cardiology such as valvular heart disease, heart failure, myocardial disease, cardiac function, and congenital heart disease. This course will familiarize attendees with recent technological advances in the field. New topics such as 3D imaging, strain imaging and interventional imaging are unique aspects to be discussed during the course along with appropriate use in the operating room, hemodynamic evaluation including cardiac emergencies, in the emergency department, cardiac catheterization laboratory, critical care units and in operating rooms will be discussed.
    4. Transfusion Medicine Update Conference
      November 18-19, 2022 • Grand Hyatt Abu Dhabi Hotel and Residences Emirates Pearl

      On behalf of the organizing committee, we are delighted to invite you to the “Mayo Clinic – SSMC Transfusion Medicine Update Conference” to be held on 18th-19th of November 2022, at Grand Hyatt Hotel in Abu Dhabi, UAE.The program is designed to deliver updates in the field of blood banking, blood donation, apheresis and cellular therapies.This conference targets all medical professional; including physicians, nurses, scientists, and medical technologists.The two days event will bring together the foremost thought leaders and experts in transfusion medicine from the USA, Europe, the GCC region, and the UAE to present data on multiple topics, including the latest developments in clinical transfusion medicine, laboratory practices, immunohematology, donor and blood supply, patient safety, cellular therapies and the latest updates in Apheresis.
    5. 6th International Bladder Cancer Update
      November 18-20, 2022 • The Westin Kierland Resort and Spa

      The International Bladder Cancer Update (IBCU) is a CME conference focused on the diagnosis and treatment of bladder cancer. The conference offers medical professionals an opportunity to listen to updates from, and interact with, expert international faculty to improve knowledge and determine best treatment practices to improve patient outcomes. IBCU encompasses expert lectures, interactive discussions, a panel roundtable, debates, and case presentations. It is physician-led, multi-supported, and designed for urologists, urologic oncologists, and other healthcare professionals involved in the treatment of bladder cancer.
    6. 2nd Global meeting on Diabetes and Endocrinology
      November 21-23, 2022 • Paris,France

      Scientex Conference is cheerful to declare that “2nd Global Meeting on Diabetes and Endocrinology” has been declared on November 21-23, 2022 in Paris, France with the success of Diabetes & Endocrinology 2021 conference.
      Theme: Modern medical research and application on diabetic condition & endocrinology function

    7. Pharmacovigilance World 2022 Virtual Conference
      November 22-23, 2022 • Online Conference

      The Pharmacovigilance World 2022 – Virtual conference will provide a platform for the participants to discuss, share and stay updated with present state of affairs in Pharmacovigilance and Drug safety, and how it contributes to the public health. It will also allow all its participants to interact with the experts, discuss the various developments, challenges faced and innovations in the field. Our Pharmacovigilance conferences are known for bringing the world-class leaders together to connect, learn and network. The conference will bring-forth the participants and the representatives from various fields of pharmacovigilance and drug safety under a common umbrella, and will provide them an opportunity to network with various industry professionals including pharmaceuticals, biologics, devices, CROs and PV service providers. It gives us a great pleasure in welcoming you to the Pharmacovigilance World 2022 – Virtual conference.
    8. 2nd Rare CNS and Neurodevelopmental Drug Development Summit
      November 28-30, 2022 • Boston, MA

      With further clinical data emerging, drug development for rare CNS and neurodevelopmental disorders is advancing from hypotheticals to real-life clinical results, outcomes, and functional biomarkers; catapulting this critical field forwards to change patients’ lives. The 2nd Rare CNS & Neurodevelopmental Drug Development Summit is the definitive industry-dedicated forum for large pharma, biotech, academia, and patient advocacy groups, paving the way towards symptomatic and successful disease modifying treatments. Tightly focused on industry progress, join stakeholders exploring ASOs, gene therapies and small molecules across autistic syndromes and seizure phenotypes in at this unique drug sponsor conference.
      November 29-30, 2022 • Santa Clara Convention Center, CA

      BIOMEDevice Silicon Valley, formerly known as BIOMEDevice San Jose, returns this winter. As Silicon Valley’s must-see regional event, biotech engineers and cutting-edge companies come together to preview the latest innovation in biotechnology and the solutions that are further pushing the boundaries of the industry.
    10. 3rd CRISPR 2.0 Summit 2022
      November 29-December 01, 2022 • Hilton Boston, United States

      Recognised with a Nobel Prize in 2020, CRISPR has opened the floodgates for a new era of gene editing therapies, promising to transform genetic disease treatments. With a well-established early field of genomics research, drug developers and researchers have been busy establishing the next-generation CRISPR toolkit, including Cas nucleases, base and prime editing technologies, and innovative delivery platforms. The CRISPR 2.0 Summit is devoted to showcasing only the latest and greatest innovations by uncovering how the next generation of CRISPR tools are radically enhancing efficacy, minimizing off-target effects and enabling efficient tissue-specific delivery to help you progress your program into and through the clinic.
    11. AI in Clinical R and D Summit
      November 30, 2022 • Virtual
      At the AI in R and D Summit, we will be gathering dedicated leaders across the globe to share experiences and the latest AI and Machine Learning techniques to increase the effectiveness in risk-based quality management, improve patient recruitment and engagement, enhance patient monitoring and safety, improve site selection, and better overall study quality and operational efficiencies – and that\’s just the tip of the iceberg. AI and Machine Learning strategies are redefining the clinical development cycle like never before. As the industry leaps into new frontiers, digital transformation is leading the way to incredible advancements that will revolutionize the space forever. At this event, you have the unique opportunity to hear from other industry colleagues about how AI and ML offer the potential to improve the success and efficiency of clinical research, increasing its positive impact on all stakeholders. – Utilize Artificial Intelligence (AI) technology, combined with Big Data, to solve key clinical trial challenges – Harness the power of Artificial Intelligence and Machine learning to transform how clinical trials are conceived, designed, and conducted – Learn how AI/ML strategies help ensure data integrity to meet safety and efficacy standards and pass regulatory review – Understand the role of machine learning in clinical research to help improve the success, patient-centeredness, and efficiency of clinical trials – Applying artificial Intelligence to reduce clinical trial cycle times while improving the costs of productivity and outcomes of clinical development
    12. 3rd Dry AMD Therapeutics Summit
      November 30-December 2, 2022 • Revere Hotel Boston Common

      2022 hosts the race between IVERIC Bio and Apellis for regulatory approval of the very first marketable dry AMD treatment. In addition to clinical advances, the field will see plenty of technology advances for more patient-compliant therapeutics, with the favourable one-dose gene therapy approach addition to pipelines, and optimized biomarker technology. Join our 30+ expert speakers as we tackle the most critical roadblocks preventing your drugs getting the patients who need them. With companies such as Janssen, Apellis, Novartis, IVERIC, Genentech, AbbVie and more, we\’ll delve into the role of genetics, subretinal drusenoid deposits, lipid peroxidation and soft drusen in the progression dry AMD; realize the future of next generation biomarkers such as OCT technologies for novel structural endpoints and pharmacodynamic biomarkers such as DKK3 to; discuss better utilization of animal models and novel patient derived iPSC models to overcome translational challenges such as poor recapitulation of the human eye and much more content.
    13. Desert Foot Limb Salvage and Medical Surgical Podiatry Wound Care Conference 2022
      November 30 – December 3, 2022 • Sheraton Phoenix Downtown

      The Live In-Person Desert Foot Multi-Disciplinary Limb Salvage and Wound Care Conference returns to Phoenix, Arizona at the Sheraton Phoenix Downtown, November 30 – December 3, 2022, after being PRESENTed virtually for the last 2 years. The renowned lecture program will be taught by some of the finest teachers in podiatry and will be focused on evidence-based, best practices to improve limb salvage techniques, advanced wound care skills, and treat surgical and medical disorders of the lower limb. The conference provides a great opportunity for you to learn along with a large part of the federal service wound care and surgical community, as well as hundreds of healthcare professionals in acute care, home care, and the private sector.
    14. Pre-Filled Syringes & Auto-Injectors Forum 2022
      December 01-02, 2022 • San Diego, CA

      Projected to hit $8 billion by the end of 2024 in the US alone, the market for pre-filled syringes and auto-injectors continues to expand at an impressive rate. Numerous advantages such as ease of administration, enhanced safety, reduced risk of contamination, and accuracy of dosing, have made PFS & auto-injectors attractive over other delivery systems. Growth in the biologics market, rising preference for self-administrations which use pre-filled syringes, pen injectors, and autoinjectors, are propelling the growth of the market. This is why you cannot afford to miss Pharma Ed Resources’ Pre-filled Syringes & Auto-injectors Forum. This two-day summit brings together thought-leaders and key decision makers to illuminate current and future trends in this key market.
    15. FAAM-EuroBAT – Food Allergy and Anaphylaxis Digital Conference, 2022
      December 01-03, 2022 • Digital

      Welcome to FAAM-EUROBAT Digital 2022. We are excited to host the key focus meeting in Food Allergy Anaphylaxis Meeting (FAAM) and the European Consortium on Application of Flow Cytometry in Allergy (EUROBAT) as a joint event over 3 days: 1st-3rd December 2022. This will be a fully online meeting, which we hope will give the opportunity for more participants to join from around the world.
      December 04-08, 2022 • Disney’s Yacht Club Resort, Florida

      National Diagnostic Imaging Symposium is designed to meet the educational needs of radiologists whether in general or specialized care and radiology residents/ fellows who desire to learn, in depth, how to use imaging in a clinical practice including night and weekend call setting for screening, diagnosis and staging of injury and disease.
    17. Lipid Nanoparticles Immunogenicity and Toxicity
      December 6-8, 2022 • Boston, MA

      Enhance Your Prediction of PKPD, Accurate Dosing Regime & Immuno-Modulation of LNP for Long-Term Patient Safety & Potency
      Following the success of LNP-mRNA vaccines, we have seen an influx of novel types of lipids based nanocarriers over the last 12 months, progress has been made to minimize immuno-toxicity challenges – from maximizing therapeutic window to fine-tuning the immune response. The highly anticipated Lipid Nanoparticle Immunogenicity & Toxicity Summit takes place this December to unite 80+ senior leaders as the definitive meeting for clinical pharmacology, immunogenicity, bioanalytical development leaders to stay at the forefront, arming you with practical takeaways and lessons learned.
      Drug & Medical Device Litigation

      December 06-07, 2022 • New York Marriott Marquis, New York, NY

      Be a part of the flagship conference that sets the standards for drug and medical device product liability litigation practice.
      ACI’s Drug and Medical Device Litigation conference has united the greatest minds of the pharmaceutical and medical device product liability defense bar for over a quarter century. Designed for masters-level strategy sharing and bringing together hundreds of industry leaders each year from both in-house, private practice, and government, this is the only forum where you can gain essential winning life sciences product liability litigation strategies. We invite you to join us this December to meet and reconnect with colleagues and acquire invaluable tactics to surmount the latest litigation challenges being faced by the drug and medical device products liability defense bar. Be part of a community of peers fighting the same litigation challenges with a goal of keeping safe and effective therapies on the market for the patients, who rely on them.
    19. Medical Wearables 2022
      December 06-08, 2022 • Virtual

      Medical wearables are the next big thing. History will show that FitBit and Apple Watch are just the early primitive devices, and that the next wave of smart medical wearables will revolutionize healthcare and dramatically improve quality of life. What are the next-generation medical wearable technologies? What are the most promising use cases and applications? What are the main challenges right now? What’s on the roadmap of the leading companies and R&D groups? These are the key questions that will drive the discussion at this annual conference. The future is bright for medical wearables — we invite you to attend this conference to identify emerging technology and application trends, exchange ideas, form new companies, and network with your industry peers!
    20. 11th Annual Predict: Tumour Models London
      December 07-08, 2022 • London

      With next generation of complex immuno-oncology candidates, preclinical and translational scientists in the IO space are in need for more predictive tumour models to improve clinical translatability, accelerating speed-to-clinic with confidence. We are excited to finally reunite this community in December at 11th PREDiCT: Tumour Models London Summit to address the critical next step of narrowing the preclinical gap and progressing efficacious candidates to the clinic. This much-anticipated in-person meeting will unite 120+ pioneers to help you: Benchmark against peers\’ in vivo and in vitro model selection strategy for novel IO, in conjunction with NK and macrophages interaction with TME, to maximise translatability Evaluate and compare next generation tumour models for TME, cell-cell interaction, immune response and drug response to guide clinical design and patient selection Accelerate off-the-shelf humanised and PDX model development for NK, allogenic cell therapies Rigorously test, characterise, validate novel cancer models to support adoption and ensure quality control in preclinical studies Engage with leading academics and CROs to drive long-term partnerships and fuel model innovations This is your must-attend tumour model summit to reconnect with fellows from Pfizer, Sanofi, GSK, and propel your clinical progression with confidence in 2023!
    21. Development and 3-D Modeling of the Human Brain
      December 07-10, 2022 • Cold Spring Harbor Laboratory, Huntington, USA

      We are pleased to announce the third Cold Spring Harbor Laboratory winter conference on Development and 3D Modeling of the Human Brain. The goal of this meeting is to bring together researchers from diverse fields to discuss advances in neural differentiation of pluripotent stem cells, including 3D brain organoids and assembloids, and their contribution to the understanding of human brain development, evolution and disease.
    22. Fearless Women Leaders in Life Sciences Summit
      December 08, 2022 • Virtual

      A focus on Women’s Leadership in the pharmaceutical industry is more important than ever before. With a heavy focus on diversity and inclusion within industries, women are a unique group making big changes within the landscape. Not only are there many amazing women leaders within the pharmaceutical industry, there are many amazing people cheering for and supporting them along the way. Promoting women in leadership positions not only embraces diversity but also helps to break barriers to open new doors for anyone looking for opportunities within this industry. As women are usually 80% of the life science decision markets, it is noticed that women have distinct needs, and it’s time that healthcare and industry leaders take a more active role in the promoting and encouraging women as leaders.
    23. 19. AIO-Herbstkongress 2022-Update Medical Oncology
      December 8-10, 2022 • Berlin

      As in previous years, the congress is all about clinical research work in the field of solid tumors and translational research. The content of the AIO Autumn Congress is designed by the working and study groups of the Working Group on Internal Oncology in the German Cancer Society (AIO). He mainly deals with the scientific update and the advancement of the AIO study activities. The format of the AIO Autumn Congress with its working and study group sessions, symposia and discussion rounds has proven its worth. This is made clear not least by the increasing number of participants and an extensive accompanying industrial exhibition.
    24. 20th Annual Emergency Medicine Symposium – A Practical Update
      December 09, 2022 • Four Seasons Hotel Los Angeles at Beverly Hills, 300 South Doheny Drive, Los Angeles, CA

      The 20th Annual Emergency Medicine Symposium: A Practical Update is a cutting-edge course that will provide participants with the latest clinical information to support the delivery of fast and accurate diagnoses and treatment decisions. Expert faculty will share their broad knowledge and clinical expertise, energy, and commitment to emergency medicine. This one-day activity will cover current and emerging trends in the emergency department (ED) and will include content on modern resuscitation, current hot topics will include non-opiate alternatives to pain management, best practice management for atrial fibrillation and flutter often seen in the emergency department. We will begin to explore and possibly define long COVID and PASC. An expert in ultrasound will teach us how transesophageal echo can be done and used by emergency physicians to asses quality of resuscitation.
    25. UCSF 17th Annual Conference Sports Medicine for Primary Care
      December 09-10, 2022 • Mission Bay Conference Center

      This conference is tailored to the front-line primary care provider. This includes primary care physicians in family medicine, internal medicine and pediatrics; followed by physical therapy, athletic trainers, resident physicians and medical students interested in sports medicine, nurse practitioners and physician assistants. Because musculoskeletal problems are one of the most common medical problems that these practitioners see in clinic, PCPs would benefit from having high confidence and competence in this area. This conference is aimed at improving the knowledge, attitudes, and skills of PCPs when caring for musculoskeletal problems.
    26. Echo on Marco Island: Case-Based Approach
      December 12-15, 2022 • Marco Island Marriott Beach & Golf, Marco Island, FL

      The program seeks to address competence in using multiple echocardiographic techniques in assessment of cardiac structure and function in adult acquired or congenital heart disease. This will include concise, limited didactic lectures with major emphasis on a series of illustrative cases which will include audience response and discussion presented by echocardiography specialists which would lead to enhanced patient management. Workshops will be held to demonstrate the techniques for acquiring the echocardiographic data, especially with respect to new contemporary techniques such as strain imaging.

      December 23, 2022

      Health, its personal. The future of personalizing nutrition as medicine. Join Genefitletics CEO- Sushant Kumar & head of scientific advisory- Mr.Rupinder Singh as they guide us through exciting growth of precision health & integrative medicine. Walk away with a deeper understanding of why feeding our microbiomes right holds answers to our most pressing chronic health issues right from metabolic diseases such as diabetes, chronic kidney diseases, hyperlipidemia, mental health issues such as Autism, ADHD, Parkinsons, Dementia, Skin issues such as Acne, Psoriasis, auto immune disorders such as food intolerances, Hashimotos, female health issues such as UTI, recurrent infections, preterm births to cancer.
    28. Cellular and Molecular Bioengineering Conference
      January 02-06, 2023 • Hyatt Regency Indian Wells Resort & Spa, Indian Wells, USA

      “Cell State Transitions in Development, Disease, and Regeneration”
      This year’s theme is intended to disseminate and integrate new advances in mechanobiology, developmental biology, single-cell technologies, bioimaging, and synthetic biology, with the ultimate goal of engineering better biological systems to transform our understanding of the rule of life, as well as translating discoveries in ways that ultimately benefit human health. Recently, many new advances have been achieved in these areas, allowing us to develop integrative approaches in understanding cell state transitions in development, disease, and regeneration. Within this central theme, investigators from diverse fields will come together in one room to exchange ideas and brainstorm new integrative strategies for pushing this field forward.
    29. Orthopedics Today Hawaii
      January 08-12, 2023 • Grand Hyatt Kauai Resort & Spa, Koloa, USA

      Don’t miss this single program that covers your entire orthopedic practice! Join an innovative exchange with nationally renowned faculty to gain a new perspective on emerging data, technology updates, surgical advances, clinical insights and practice management tips. Plus, our location and casual atmosphere allow attendees to comfortably earn CME and interact with peers in a beautiful setting.
    30. RNA Nanotechnology Conference
      January 08-13, 2023 • Four Points by Sheraton Ventura Harbor Resort, Ventura, USA

      The RNA Nanotechnology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
      January 11-12 2023 • London, United Kingdom

      With the injectable drug delivery industry growing exponentially year-to-year, administration using pre-filled syringes, auto-injectors, and pen-injectors are increasingly common. Innovations in device technology, such as smart devices are leading the way in device design in addition to injectable delivery devices for novel and long-acting therapeutics. We are starting to see environmental sustainability being incorporated into aspects of device manufacturing, design and the use of the device. This year’s conference looks to address the hot topics of the injectable drug delivery industry through case studies and industry insights. This event will not only bring you key insights you need to expand and enhance your injectable device portfolio but will also give you the opportunity to network with key players throughout the industry. We hope to welcome you to this must attend event in January 2023.
    32. 11th Annual Pharmaceutical Microbiology Conference
      January 16-17, 2023 • London England United Kingdom

      Co-chairs Di Morris, Clinical Auditor, AstraZeneca and Nigel Cryer, Deputy Director Global Audit, Sanofi We are delighted to announce SAE\’s 11th Annual Pharmaceutical Microbiology conference taking place in London, UK on the 16-17 January 2023. Microbiology remains an essential tool for the detection of microorganisms present in biopharmaceutical and pharmaceutical batches. This conference will explore the most pressing topics in this thriving field, from the movement toward process automation and increased regulatory stringency, to the latest technologies in rapid microbiological testing methods and data integrity. Key Highlights for 2023 Conference: – Optimise your contamination control strategy and review the initial impact of Annex 1 – Learn how to utilise the latest microbiological methods to modernise your contamination control strategy – Maximise the data output from your environmental and microbial monitoring with proven strategies and technologies – Increase the diversity of your testing methodologies through industry case studies including the recombinant factor C assay and Monocyte Activation Test Who Should Attend? Heads of Microbiology, Heads of Aseptic Processing, Global Quality Directors, Heads of GMP Compliance, Quality and Compliance Heads, Microbiology Senior Specialists, Directors of Quality Control Biology, Quality Control Managers, Quality Assurance Managers, Lean Managers, Operations Managers, Heads of Site Compliance, Heads of Sterile Technology, Global Microbiology Analytical Experts, Cleanroom Managers, Regulatory Affairs Managers, Production Managers, Quality Systems Managers
    33. Transdermal and Microneedle Drug Delivery Conference
      January 23-24, 2023 • London, United Kingdom

      SAE Media Group is proud to present the 2nd annual Transdermal and Microneedle Drug Delivery Conference, taking place on the 23rd to 24th January 2023.The 2023 Transdermal and Microneedle Drug Delivery Conference will explore real world applications of microneedles in drug delivery and strategies for advanced and user-centric device design. Regulation of transdermal delivery systems will be another key theme addressed, in combination with clinical trial optimization. Engage in the latest innovations in device design, development and formulation, with case studies from expert key opinion leaders of this rapidly accelerating space. Other key areas will be microneedle vaccines and transdermal patches for management of chronic disease.
    34. RNA Cell Therapies Summit
      January 24-26, 2023 • Boston, MA

      RNA technologies have taken the world by storm over the pandemic and now the potential to of RNA engineering to enhance cell therapy is finally being realized. The therapeutic potential of RNA cell therapies is huge, but challenges remain in cell-specific delivery, improving durability of responses, demonstrating safety and elucidating regulatory considerations to deliver for patients. The inaugural RNA Cell Therapy Summit is the first of its kind to unite 80+ industry and academic pioneers from both the RNA and cell therapy field to bridge-the-gap between transient RNA engineering and cell therapy development.
    35. 6th DDR Inhibitors Summit
      January 24-26, 2022 • Boston, MA

      DNA damage response inhibition has amassed a lot of interest over the last decade as it exposes a massive vulnerability in cancer cells. This has a huge potential to treat many types of tumors such as breast and colorectal cancers, and even notoriously difficult-to-treat CNS tumors. The 6th Annual DDR Inhibitors Summit will cover both the preclinical and clinical DDR inhibitor landscape and establish how the field is addressing the biggest hurdle to drug development – toxicity. From reviewing progress with both novel and established targets to utilizing inhibitors in combination studies and improving patient selection with improved biomarkers; this meeting will give a comprehensive and up-to-date overview of the field. As we look to 2023 and what it has in store, this highly anticipated summit is back in person, bigger and better than ever before. As the industry-leading conference, join forward-thinking researchers from the pharmaceutical, biotech and academic community as they unite to share ideas on progress, challenges and novel solutions in the current DDRi climate.
    36. Molecular Glue Drug Development Summit 2023
      January 24-26, 2023 • Boston, US

      Built with biopharmaceutical industry insights, this in-person meeting will bring together KOLs to delve deep into the key remaining challenges when it comes to identifying, designing and developing the next generation of molecular glues and truly unlock the widespread therapeutic potential of this promising therapy. This forum will deliver exclusive data from the movers and shakers in the molecular glue space, from the likes of C4 Therapeutics, Monte Rosa Therapeutics, Amgen, Proxygen, Pin Therapeutics, Degron Therapeutics, Plexium and more. As we continue enriching the design and development of molecular glues, network with 80+ leading Chemists, Biologists, Bioinformaticians, Structural Scientists and Computational Chemists at the world\’s first-of-a-kind meeting to successfully accelerate the first wave of molecular glues into the clinic.
    37. Hybrid Course! 2023 Cedars-Sinai International Endoscopy Symposium
      January 26, 2023 • Virtual

      The Cedars-Sinai International Endoscopy activity will offer an intensive and comprehensive review of pancreatic and biliary endoscopy for the benefit of gastroenterologists, gastroenterology fellows and gastroenterology nurses and technicians. Invited expert faculty will perform multiple live luminal endoscopy, EUS and ERCP procedures to demonstrate techniques and technology for the benefit of participants watching the live feed. Participants will be encouraged to ask questions virtually about what they are viewing through the session moderator. The activity will focus on live procedure demonstrations covering endoscopic interventions for IBD and esophageal conditions, innovations in endoscopy and endoscopic closure, stapling content and multiple live ERCP and EUS demonstrations. Balanced viewpoints, special techniques, and practical clinical approaches will be highlighted throughout the activity.
    38. 7th ICRS Surgical Skills Course / Wet Lab Doha 2023
      January 26-28, 2023 • Doha, Qatar

      At the end of the year 2022, Doha will be the center of the football world with the FIFA World Cup 2022 held in Qatar! At the beginning of 2023, from January 26 to 28, Doha will also take world center stage of the cartilage restoration and joint preservation community with the organization of the 7th ICRS Surgical Skills Course and Wet Lab, taking place at the Aspetar Orthopaedic and Sports Medicine Hospital, a FIFA accredited medical centre of excellence.
    39. 35th Annual Selected Topics in Internal Medicine 2023
      January 30 – February 03, 2023 • Koloa, HI US

      Mayo Clinic’s Selected Topics in Internal Medicine (STIM) is a postgraduate course designed to update general internists, internist-subspecialists, family medicine specialists, and other primary healthcare professionals on selected internal medicine topics. Some of the most common problems encountered in clinical practice are represented. Course focus is clinical pearls and practice updates. Presentations are made by experts from various disciplines in internal medicine and faculty members are available during breaks to answer questions and to discuss cases with course participants.
    40. Viral Vector Process Development Summit
      January 31-February 2, 2023 • Boston, MA

      As cell and gene therapy and genomic medicine pipeline continues to mature, process development for viral vector is becoming critical for drug developers for the next phase, to deliver a quality, transformative cure to patients with affordability. The recent investments such as Novartis-Samsung Biologics $81m contract for viral vector manufacturing, Resilience raising $625m towards biomanufacturing capabilities including stable cell lines for viral vector production pave the foundation for scientific and technology innovations.With better understanding of these novel nanoparticles, developability and cell line development, the ability to optimize AAV, LV formulation and define robust CQAs are critical to drug developers’ ability to increase scalability with efficiency, reduce cost of goods and most importantly, ensure product quality control for patients.
    41. Structural Heart Intervention and Imaging 2023: A Practical Approach
      February 01-03, 2023 • Hyatt Regency La Jolla At Aventine

      This CME conference will consist of live case demonstrations, didactic lectures, workshops, and satellite symposiums focused on LAA closure, TAVR, mitral and tricuspid repair and replacement and more!
    42. Comprehensive Shoulder and Elbow: Current Concepts and Controversies 2023
      February 02-04, 2023 • Scottsdale, AZ US

      This course provides information on the latest treatment options for shoulder and elbow arthroplasty, arthroscopy, fracture and reconstruction. The focus is on the best current practice in diagnosis, treatment and new technology. Faculty with international expertise in shoulder and elbow surgery discuss how to optimize surgical techniques and how to avoid complications. Didactic sessions emphasize tips and pearls to approach complex shoulder and elbow reconstruction. Attendees are encouraged to bring cases for discussion.
    43. Clinical Data Disclosure and Transparency Summit
      February 15-16, 2023 • Virtual

      Adhere to new clinical data disclosure regulations from the US and EU by understanding all parts of the transparency process and avoiding public misunderstandings and penalties. The CTIS regulations alongside FDA regulations has given the clinical data disclosure and transparency landscape a renewed interest for professionals and requires a space for discussing best practices regarding global regulations going forward. This summit will explore how to quickly create experts in any sized organization on these clinical data disclosure policies and discover how to be confident in earlier disclosure of clinical trials.
    44. 11th Annual Acute Care of the Complex Hospitalized Patient for NPs And PAs
      February 15-18, 2023 • Scottsdale, AZ US

      As hospital care models continue to evolve; NPs and PAs are playing an increasingly vital role in the care delivery of hospitalized patients. This conference focuses on providing the most up-to-date, evidence-based guidelines and treatment pathways necessary to optimally care for hospitalized patients. The course covers topics in critical care, hospital general medicine, surgery, neurology, hematology, cardiology, psychology, pain management and other medical subspecialties and features multiple options for skills workshops to further tailor the educational needs of NPs and PAs.
    45. Clinical Hematology and Oncology 2023
      Februay 18-20, 2023 • Hyatt Regency La Jolla At Aventine

      The 2023 Clinical Hematology and Oncology Conference, presented by Scripps MD Anderson Cancer Center, is designed for hematologists, oncologists, surgeons, radiation oncologists, internists, and others desiring an update in these specialty areas. The primary objective of this course is to bring together clinicians and leading experts in diverse areas of hematology and oncology, affording them an intimate environment in which to discuss new clinical developments and significant advances.
    46. 32nd International Conference on Nursing & Healthcare
      February 20-21, 2023 • Las Vegas, USA

      The dashboard of Google Analytics traffic overview of “32nd International Conference on Nursing & Healthcare” clearly reflects the interests of the global enthusiastic conference attendees like Presidents, CEO’s, Clinical Nursing, Nursing scientists and researchers in Nursing, Delegates and industrial executives from nursing and healthcare industries, Nursing Education from around the globe who are searching to attend and present/exhibit their research/organization findings on highly acknowledged international conferences like ours with the web traffic a total of about 2,25,455 visits. The total page views were close to 4,43,995 where our reports are analysed half yearly.

    47. 2nd GPCRs – Targeted Drug Discovery Summit 2023
      February 21-23, 2023 • Boston, MA

      We are delighted and extremely glad to announce our Webinar entitled “International Webinar on Global Healthcare” will be held on May 29-30, 2023. The program will grab on both international and regional speakers’ who are experts in Healthcare and Medicine knowledge. Topics would be focused on common and updated scientific knowledge with the theme of “To explore the advanced and emerging techniques in healthcare”.
    48. Pain Management for the Non-Pain Specialist
      February 23-25, 2023 • Scottsdale, AZ US

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      March 20-21, 2023 • San Francisco, USA

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      March 24-25, 2023 • Epic Sana Lisboa

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2022 Keynote: How Dave Albert (AliveCor)
Innovates in Medical Devices and Wins

26 min reading time
How Dave Albert Innovates in Medical Devices and Wins
Presented by Dr. David Albert, AliveCor
at the 10x Medical Device Conference – San Diego, 2022

Joe Hage: What I enjoy most about him and I know you’re all gonna say the bowtie, it’s not the bowtie, he is sartorially splendid, and he’s really smart and really rich.


Joe Hage: He has 72 patents.

David Albert: : 80

Joe Hage: Pardon me. I didn’t look this week.

10x London is on! Join us 15 September 2022.

Joe Hage: And I know of very few manufacturers who have gotten things off the ground and commercialized the way he has. Every moment I speak is a moment you’re not listening to him. Here’s Dave.

Dave Albert: It’s a big pleasure for me to be here. It’s a real surprise. Because back in 2001, a company called General Electric bought my second company, I started, named Data Critical.

And while I was there, which was for about three-and-a-half years, I had a boss – my best boss(!) – and he’s sitting right there, named Claude Benchimol, and I have not seen him in way over 10 years. So I would – he said, “Don’t you recognize me?” Yes, I recognized him, which was good! And I didn’t have to look at his nametag. But that’s, that’s an extra special pleasure. It’s a pleasure for me to be here. You know, I’ve had a number of you come up and ask questions. And that’s kind of why I’m here. Ask questions.

I’m old now. So, Claude, you know what that means about you. [Laughter]

I have a lot of experience in medical devices. Now my experience is really focused on cardiovascular medical devices. It’s not a small area, it’s actually a huge area. But it’s, it’s certainly not area, and many other types of medical devices.

But you will see the world from my perspective, and I’m gonna go through, you know, I’ve got slides, and I’ll go through them. If I was you, buckle your seatbelt, it’s gonna be a wild ride.

But what I’m going to do, is I’m gonna go through innovation, invention, the things you have to do that you’ve heard people talk about today – regulatory? Oh, my God! And protecting intellectual property, oh my goodness!

And for those of you who know, I’m just suing the world’s biggest company – three separate lawsuits. I’m going to win, by the way. So that’s scary.

It’s really scary to do things like that, to be deposed for eight hours, by a really mean attorney.

But it’s what you have to do if you’re wanting to protect the things you’ve developed. And, and in medical devices, you know, we develop intellectual property. So I’m gonna go into that, and then I’m gonna talk about – the last part of it is how you get your things accepted.

Because I can get patents and build devices. I can get them through the FDA, but I have to get customers to buy them. And how do you do that in medicine?

Now, why am I here? That’s that’s an interesting notion.

I started four companies that make life-saving devices, sold a couple of them – sold one to General Electric. I said Benchimol, I said Dr. Benchimol there was my boss for awhile. I raised over $500 million, both private and public equity. Anybody here ever heard of a guy named Vinod Khosla? He’s the Chairman of my Board. He’s only on two boards, Square and AliveCor, and he’s my chairman.

But we also have Qualcomm, little company here in San Diego, Mayo Clinic, fairly well-known healthcare enterprise, and a Japanese company named Omron, and if you go and buy a blood pressure cuff, you’ll buy theirs.

So those are some of our investors.

I have 80 patents – 30 international patents – taking at least 20 devices through the FDA. We’ve sold over 2 million devices. We have about 1.2 million active customers right now. How do I know that?

We get a million ECGs into our cloud. So one of the smart things – I’m not very smart – one of smart things I did when I started this company in 2011, when you sign up with us, you sign away your rights to anonymized data.

So I get every piece of data – it goes into AWS. And you’ll see I have a I get a million ECGs every week, there in my cloud.

You’ve heard of the saying “Big Data?” “Machine Learning?” Yeah, we got that.

And then we’ve raised many millions already.

Innovation, we still need it. Things are getting faster. There’s an organization, Exponential Medicine, if anybody’s ever been to the meeting, a friend of mine Daniel Kraft ran it – was always at the Hotel Del, and he talks about this notion of Singularity University and things are getting faster and faster. It’s absolutely true.

I mean, one of the greatest examples are the mRNA vaccines. The fact that they developed a vaccine using a technology that never been used before, in a year or less than a year?! Just unbelievable. So interconnectedness.

Anybody here not have a smartphone? You wouldn’t admit it if you didn’t.

Joe Hage: Any of you wish you DIDN’T have a smartphone? Yeah, exactly. [Laughter]

Dave Albert: But we’re always connected. And that can raise can raise its own problems, but it means the world is connected.

You know, we’re all connected, whether it’s social media, which is both positive and negative in terms of connecting us, or whether it’s these things in our pockets.

We seem to stay connected. I don’t know what we did 20 years ago, Claude, how did we, you know, email was relatively new. And today we have Slack, we… it’s just amazing… WhatsApp.

So the pace of a viral epidemic can be frightening. We saw it. If you are New York in March, in April of 2020, you saw what the pace of a viral epidemic can be.

And I was the beneficiary of a viral epidemic. I made a four-minute video, December 30, 2010. And I just happened to upload it to my 400 LinkedIn followers, I have 13,000 LinkedIn connections now, but I had 400 at the time, and I went home to have a date with my wife on New Year’s Eve. And by Saturday, and I had 400,000 views. That was in 2010, okay?

I got called by… so I went to the Consumer Electronics Show. And I got a call from everybody from Apple to CNN and Fox and Friends and Good Morning America. And I had to get up at three in the morning. So I could be there at four in the morning. So I could be on the air at seven in the morning. And it was my video went viral. Now I was in my mid-50s, I had no idea what was going on. But I was the beneficiary of a viral information spread.

We know as a medical doctor, viruses, this is the 1919 Spanish flu. And by the way, if this were 1919, this would have been just as bad. SARS COV-2 would have been just as bad as the Spanish flu. And, you know, we’re lucky that we have the science and the medicine we have today.

So exponential medicine, you know, the sigmoid curve, things don’t just move in straight lines. This is this is biology, this is real life, what they add on top of each other something we enter in engineering called superposition. And you can innovate anything. Anybody have a Nest thermostat, or an equivalent? Now we do. And that, you know, you can control your temperature and your air conditioning and heat from wherever you are with that smartphone thing that’s interconnected.

Everything is connected your cars, right, your Tesla, you can start it, you can stop it, you can tell it to park and come get you. So we’re all connected.

And so, is planning to invent an oxymoron? How do you plan to innovate?

Well, you can, there are things you can do. I’m not seeing a lot of people doing well. And I’ll go over some of them. These are these are a few.

One thing I talk about is thinking orthogonally. And for those of you who don’t remember your basic geometry, orthogonal means at a 90-degree angle, okay?

So, when conventional wisdom is, as an example, a vector in that direction, orthogonal would be pointing in this direction. It means taking a different view than everyone else, taking a different perspective than conventional wisdom.

And the other thing is intercepting the strategic vector, where are things going? You know, 20 years ago, we had a book called Megatrends by Naisbitt and talked about the trends that have taken off. Well, now we have social media. I mean, tik tok. You know, I can tell you that Mark Zuckerberg is scared of tik tok, you know, and he bought Instagram, and he bought WhatsApp, he bought the things that he thought were going to jeopardize his facebook business. And then here comes the Chinese, with tik tok. And I would tell you, it’s addictive. It’s amazing. And they, they scared him. So orthogonal thinking, I talked about that.

Ignore the conventional wisdom, you may fail, but don’t be afraid of failing. Okay, that’s one thing. Steve Jobs said over and over again. If you’re afraid of failing, then you shouldn’t try to be an entrepreneur, innovator.

Smartphone. It is the portal to healthcare. About eight years ago, I had a guy from Kenya – anybody here ever heard M-Pesa? M-Pesa is the cellphone-based money they use in Kenya, they really pioneered it. And the guy gave a talk and he said, you know what we’re gonna do? We buy sugar. Let’s do bread by the slice. We’re gonna buy healthcare the same way. And I think that’s the notion, we here, we’re buying insurance, we’re worried about co-pays and deductibles . By the way, insurance they’re going? Only one direction.

Big Data and AI? I just told you, I get a million ECGs my cloud. Do you think anybody can read those ECGs? You think it’s even remotely possible that I can recruit enough experts to even begin to think about reading those ECGs? No way. So if we aren’t able to use AI, sophisticated machine learning and deep neural networks, for those I don’t want to go into a treatise here, but they’re just pattern recognizers. They’re really, really good pattern recognizers and they’ve revolutionized image recognition and speech processing. But that’s what they are. They are not general AI.

Inventing is a team endeavor. We have a bunch of people here who are in complementary jobs, complementary companies. There’s no such thing. By the way, Thomas Edison was a team inventor. He had a team in Menlo Park with people. He didn’t do it all himself. Okay. Well, that certainly is true today, when people are very specialized. We have people who have front-end developers and back-end developers and cloud and AI and hardware people and RF people, and wireless people and analog guys. It takes a team of people to invent medical devices.

Build a prototype that works well. Congratu-damn-lations. Okay, it works. Now, what do you do? Well, I’m going to go into that.

Patents? Anybody here have patents? That… good? So you know, what it’s like, it’s not inexpensive. It’s not painless. It’s not fast. It’s none of those things. And oh, by the way, what does it do? Does it really protect you? No, it gives you a right to sue somebody. Talk about a process. It’s neither fast nor inexpensive. If you think in patents, is that, litigate? Oh, my goodness. Okay. So I would tell you, that while they are probably necessary, they are not painless. And I would say evaluate whether your business is moving so fast, that the value of patents is really relatively minimal.

You need a plan. How many people here have written a business plan? Okay, so you know, today, if you go to somebody on Sand Hill Road, one of venture capitals on Sand Hill Road, and I’ve had NEA, Coastal Ventures, I can tell you, I’ve been in front of Andreessen Horowitz and Sequoia, they just want a deck. Nobody wants 15 pages of Excel spreadsheet anymore. And what I thought you needed 30 years ago, but now because they are, this is not trite, they are investing in you. And whether or not they think your idea is big enough. TAM, total addressable market, and whether or not they think you, together with the people you can recruit, and they can help you, can realize the vision in that plan. So a plan today is a deck.

Like I said, I can’t speak for, you know, urological devices, or even, you know, advanced imaging… Dr. Benchimol can… whether it’s MR or CT, I can speak about ultrasound, which is advanced imaging – has come a long way from when I was building those devices, but really I’m focused on cardiovascular diagnostics. And that’s what I’m going to use as my examples to try to give you some lessons.

So, heart disease, despite everything we’ve done, and we’ve done amazing things, is still the world’s number one killer. In certain parts of the world, it dominates. South India, skinny on the outside, fat on the inside, genetics, lifestyle, all kinds of things.

In fact, about seven years ago at the American Heart Association, the head physician from Beijing’s major heart hospital came and gave a keynote at the AHA scientific sessions. And he said, you know, we manufacture all these things in some of the United States, but you’ve exported something to us: Your lifestyle, you’re smoking cigarettes, sitting at desks, typing into computers. And so our incidence of heart disease, we’re no longer a, you know, cultural revolution, agrarian economy, we’re now in the business of having heart attacks. And so they are very concerned about that, because it’s draining a lot of resources they’ve rather commit to taking over the world.

Digital health, everybody has adopted digital health, every healthcare organization, you know, you download apps, you have your MyChart portal it’s going into EPIC.

Everybody is using those tools, why? Connecting to patients.

The idea that patients are first was never the case. You know, when you were rolled out in your wheelchair and put in a car, you know what they hoped that you came back tomorrow, because that’s how they made money.

Today? If you come back tomorrow, they’re going to lose money on yet because they’re going to be penalized. And so they’re very concerned about patients. And digital health is a way of engaging, empowering and connecting them to patients.

So in cardiovascular we have tons of devices, digital health devices, digital health apps, implantable devices, non-invasive devices, we have a lot of devices, okay. And today, we have handheld ultrasound devices.

It’s a company butterfly that’s made of business on it as good as my business but they sold the business. The big ones Philips, GE – I have a Vscan Air, it’s a handheld ultrasound device, totally wireless. So that technology will ultimately supplant that old stethoscope that we use to hallmark we’re a doctor or nurse.

So what’s our journey? Well, you know, first of all, I had a smartphone-connected device – we still do – and it is evolved. We had a, this is going to be funny. We had a first smartwatch ECG called KardiaBand. So before Apple introduced ECG built into their device, we had that device.

We then partnered with Omron, if you’re going to CVS, you can buy something called an Omron Complete. That’s a blood pressure machine with our ECG technology integrated into it. We’ve developed a number of other services.

Recently, our most recent FDA clearance was for device that’s literally the world’s thinnest ECG, the size of a credit card.

I had people from Medtronic, when I was back here, this is a Medtronic LINQ, one-third the volume of a triple-A battery. And it has a three-to-five-year battery life, they implant it under the skin records ECG, it takes four of our devices to equal the width of that device.

I had Medtronic engineers come to the Heart Rhythm Society last week, and compliment me, I take that as a real compliment.

We right now have 1.8 million active users who have recorded 150 million ECGs, all of which residing my cloud, and I get a million every week. Again, human beings cannot annotate that, cannot over read that. We must have machine learning. But that is the raw material that feeds machine learning. That’s a real asset.

And you can see kind of you see the cyclical nature? Well, that’s because we sell a lot of our devices direct to consumer and by the Amazon. Anybody here ever seen any of our TV ads?

Joe Hage: Yeah.

Dave Albert: Okay, so we have TV ads, I saw it on “60 Minutes” the other night.

Joe Hage: And that was not an inexpensive buy.

Dave Albert: But we’ve, we have built a consumer brand.

It’s amazing.

And it’s cost us about $60 million to do that. But it’s something a lot of the- I don’t think there are many digital health companies that have a consumer brand. But we spent a lot of money we made, you know, we were supported by our investors to get us to the point where that is a very valuable asset, just like our intellectual property, just like our customers, just like the data.

So with 2 million lifetime users. 640,000 people take their ECG this week, 150,000 subscribers, that is, those people paying us 10 hours a month. That means we have $17 million of recurring revenue, very important to investors.

42 countries. See, this is out of date: 150 million ECGs, 110 patents filed globally, we have about 50.

And then 185 peer-reviewed papers, and I’m gonna get to that. That is we’ve had someone today. In fact, this was an article about a paper that was published in the Journal American College of Cardiology EP. We had no idea. Let’s just say Cupertino does not Dave Albert. I’ve gotten that reinforced several times. And they’re definitely don’t like this.

Joe Hage: It’s hard to see in the back. This is dated May 9.

Dave Albert: Yeah, it was it was today. It was today. It was yesterday, excuse me, yesterday. And we didn’t know this was coming out. But our lawyers like it a lot.

So a backbone is… AI is the backbone. And we have an extensive artificial intelligence data science team, we used to call them algorithms, and now we call it data science. It’s the same thing. We use different methodologies. And we use machine learning more than experts saying, well, it should be this, you know, divide by this, this millivolts or microseconds, we let the data tell us what it should be. But when you do that, you’re going to need accurately annotated data to do some called supervised learning.

Although one of the leaders in deep neural networks, Yann LeCun, who’s both the chief scientist at Facebook and also professor at NYU, says the future will be unsupervised. And we’re taking advantage of that.

Okay. Remember, I told you the most important thing is you got to get customers to buy the dogs must eat the dog food? How do you do that in medicine?

Well, you prove your device either can do the same thing they’re doing today only to a cheaper and faster, more efficiently, or really prove that it’s better than whatever exists today. Those 108 peer reviewed publications? That’s what that’s all about. So they’re in every major cardiovascular journal.

And here’s, here’s the today. Every two weeks, we have a new paper published every two weeks. So that’s a pretty good rhythm.

Biopharma. We have partnerships with Novartis with Bristol Myers Squibb with a number of pharma companies. Anybody here ever see an ad for a drug called Kasqali. For metastatic breast cancer, every Kisqali patient gets an AliveCor device to monitor their QT because Kisqali, while it’s helping to treat your breast cancer, could kill you with a prolonged QT.

So the FDA demanded that. We have FDA clearance.

We reduce healthcare utilization. So last year, had a paper published in July 2021 that said you can reduce ER visits. Does anyone know how much an ER visit costs?

About $6,000. So if I reduce one ER visit, I just want you to give me half, you can keep half, I’ll take half. We’ve also had people recently do loading of drugs that normally have to be loaded in the hospital. Ohio Heart just presented an abstract at the Heart Rhythm Society. They said they saved using our device as an outpatient loading it remotely $6,800 per patient were saved. Again, just give me a little bit of that.

Healthcare organizations. I think I mentioned these. all the leading health care organizations in this country in Canada, in the UK, around the world, use AliveCor and we’re in 42 countries are not in China yet. We’ll be in Japan at the beginning of 2023. But we’re, you know, in many parts of the world, and recently, we got something called NICE guidance. So the National Institute for Clinical Excellence, the part of NHS that evaluates new technology – it only took us eight years – it really moved fast in England – but that means that they will pay for our device.

The National Health Service will pay for our device, a general practitioner can provide our device, that’s a big deal. And we’re expanding that around the world.

It’s all about not – the patents – the patients. That’s what I said earlier.

That’s what digital health is. Digital health is engaging the patients in their own care. An engaged patient is compliant patient and compliant patients is complying with their own treatment is a better-outcome patient. And that’s what it’s all about.

I, you know, I went in this business to help patients. We have thousands of people we’ve helped. And these are just some of them. These are just examples of people who’ve reached out to us.

I mean, I’m proud to say we’ve had well over a thousand people say thank you for saving my life, my son’s life, my dad’s life. I’ve had two people at GE Healthcare telling me the same thing.

Two people came up to me and said, you know, it was amazing. I’m sitting there trying not to cry, by the way, when they tell me this.

Here’s my personal system. This is what I have done. So first of all, this was my first patent. This was a heart rate monitor. And you think something like that existed in 1981, that’s the thing I wanted to build for my dad. I actually built that. And I sold it to Timex, okay, at the time, and today I have a relationship. That will be used an array of sensors. And, again, I built a prototype that was on my wrist.

This was the next product I licensed – this was to Quinton Instruments. Somebody here worked at Quinton? This was Exerdop. I sold that to them in 83.

And what you see on the left is from the patent. What you see in the middle is a “Circulation” paper – Circulation is the major journal of the American Heart Association. And on the right, you see the 510(k) and then you see an app.

So notice something: Patent, clinical validation, FDA clearance, commercialization.

This was my net first company, Corazonix. We built an EKG microscope: Patent, clinical validation, FDA 510(k), commercialization – used by every major company. Sold that company in 1991. This is AliveCor: Patent, clinical validation, that was a presentation to the Heart Rhythm Society – I told you I have 180 [peer-reviewed studies] – 510(k), we have a number, and then that’s a slide from my original 2010 video.

If you’ve seen our ads, you will know who we are, we sell a lot. We sell over 1,000 devices every day.

And this is device I told you about patent and 510(k), where’s the clinical validation?

Well, this, in essence, is the same device we’ve sold for 10 years. It’s just way, way, way smaller, way more convenient. I keep it in my wallet. And so while there will be clinical validation, by the way, that’s the thing that takes the most time. We did studies, which is how we got the 510(k).

Anybody seeing a theme here, I do the same thing. Again, and again, and again. I invent, I protect my invention. I get it clinically proven, so that people believe it. Then I get it regulatory – I jump the regulatory hurdles. And now I’m ready to commercialize.

And so that ladies and gentlemen, is my plan. And now I’m happy to take your questions. Thank you.

Joe Hage: I know there are questions. Steve, stand up and tell us who you are, what you do, and your question.

Steve Maylish: Steve Maylish, Fusion Biotech, we’re a contract engineering firm. A lot of people say commercialization is the toughest part of this business. Do you have any tricks of the trade on the commercialization side?

Dave Albert: Depends what you’re doing, you know, we sell both to health systems and directly to consumers. That’s part of the digital health nature. I mean ours is Class II medical devices, FDA cleared, they are ISO 13485’d, all of the medical things, yet we have FDA clearance to sell that directly to consumer, like a glucometer, like blood pressure cuff, like pulse oximeters today.

And so we skirt two ways, you know.

The problem with selling to consumers is, it’s really expensive, because you got to go build that thing called “a brand.” Selling the doctors and the hospitals, requires human beings, direct sales force, and that too, is expensive. And that’s what I’ve done previously, I had sales forces, that called on hospitals and called on doctors, just like Medtronic, Philips, GE, they have these large sales forces, Boston Scientific, Abbott, you know, that educate and sell their product or services.

And increasingly, everybody wants to sell you a service for that magic, recurring revenue. Okay. So they want to somehow turn, turn themselves into another Netflix, despite the fact they just had a bad quarter. Yeah, but despite that fact, that’s what they want to do. And so you’re gonna see more and more innovative ways, I think.

The healthcare system – because it’s so messed up in this country – so such a patchwork of, you know, uncoordinated was not designed, just happened. I think they’re gonna get smarter about why do I have these sales people that, by the way, sales people didn’t show up for the last two years, they couldn’t come into the hospital.

So they learned that, you know, they can do things, and the companies learned I can do with fewer sales people. And so I think you’re going to see some movement away from what I would call the classical direct sales model in medical devices, although you’re still gonna have major educational component, and relationships still matter.

But we do both. And I can tell you, that’s a challenge. To do both. Well, you need different people selling consumers, it’s completely different than selling to health care organizations.

Joe Hage: I have the next question. And that is, I know that success to some degree begets more success. You are proven, you did this, I trust you, I’m gonna give you money, etc. Tell us about – I know it was out of love and you made it for your dad? How much would it cost to make your first invention? And were you able to leverage that for your next invention to get investors and human resource.

Dave Albert: $500, it cost me 500 bucks.

Joe Hage: Back in the 30s that was a lot of money!

Dave Albert: It was a lot of money back in the Depression. [Laughter]

That patent my dad paid for that, that cost about $3,000. You couldn’t get a provisional patent for $3,000.

Today, forget about an issue utility US patent. And by the way, that patent has been cited so many times. I mean, who here has a wrist device that measures your heart rate? Will they all refer back to that same day, every patent refers back to that I again, I don’t know what I was drinking that night. But it was fairly, you know, prescient idea about the future.

So it thinks cost a lot of money, you know, a utility US patent today, $15,000. International coverage – not even global – $100,000. And that just gives you – if you get it – that just gives you the right to sue. And suing is a seven- to eight-figure endeavor.

And so it’s not for the faint of heart. And it’s certainly biased against small companies, individuals, it’s not set up for those.

So that’s what I wanted to ask you before leaving there and again, talking about the cases, or how they are fruit-like the competitor, may be. How do you how do you get your case together when you’re fighting a Goliath like that?

You remember what I said? I have Qualcomm, Mayo Clinic, Omron. Khosla Ventures.

Joe Hage: I’m trying to make this relevant for the people who aren’t you.

Dave Albert: We have we have deep pockets.

Joe Hage: YOU do.

Dave Albert: That’s, that’s the point. And you know, we wouldn’t take it on if we didn’t think (a) we had a very good chance, or (b) we didn’t have the wherewithal to do it.

And so, it’s unfortunate, but that’s the way the system is. And there are people who are trying to change it. I don’t know that they will.

Has anybody here ever heard of the American Invents Act? Yeah, so that changed everything. It used to be in the United States that, I kept notebooks – I have a shelf of notebooks – that would document my invention date. That doesn’t matter anymore, because the rest of the world went on ‘first to file’ not ‘first to invent.’ And so notebooks are irrelevant.

It’s when you file and the American Invents made us homogenize our system with the rest of the world. The problem is, it’s easy for a big company to file zillions of patents. And so it really bias to the system. Now there are people who fund litigation. And they are the bane of a lot of company’s existence, because they’re they’ve said they’re called ‘trolls.’ But, you know, some people would call them heroes if they’re defending their intellectual property honor. I don’t have a position on that. I’ve been on both sides, I’ve been an expert on both sides of those kinds of cases.

Well, what I will tell you is the patent system is not for the faint of heart. It is necessary yet not sufficient in order to protect your innovations. Some companies don’t ever get patents and do very well. Other companies protect their intellectual property, one down the street here called Qualcomm. You ever walked into their main building? You’ll see a wall, a huge wall of patents. And that’s because that’s they were based on intellectual property started by Viterbi, and Jacobs, to MIT professors who said, “We can do wireless better.” The Viterbi algorithm, there’s the Viterbi School of Engineering at USC by the way, and they basically said, “We can do it better.”

And the rest of world said, “Oh, that’s a joke, you can’t do it.”

And they did it. So that our all our cell phones are based essentially on an expansion of something called CDMA, code division multiplexing, as opposed to a time division, or frequency division, and theirs is better. And so they let companies become a very big company, and has litigated. They got a head start. And they were able to get, you know, get enough mass. But normally patents are are challenging to enforce against those companies.

Joe Hage: I have Andrea Davis here because she’s my “Patent Detective.” And I just wonder what your reaction or thoughts are with what David just shared.

Andrea Davis: I think it’s all very insightful. And and I’m impressed by your patent knowledge. And I think it’s something that is needed for an for an entrepreneur and a lot of people, you know, have a hard time it’s a challenging thing to to embrace, to learn to navigate. So I have all the respect.

Dave Albert: I sued and been sued. I’ve been a witness, as well as an expert. So I’ve been to the Court of Appeals, District Court, ITC. So yeah, I got – those are some of those scars I told you about?

Joe Hage: Have you ever been on the People’s Court or Judge Judy? [Laughter.]

Dave Albert: Judge Judy? I’ve not been on Judge Judy.

Joe Hage: But the People’s Court, yes?

Dave Albert: No.

Joe Hage: Amy has the next question.

Joe Hage: Hi, Amy Asbury, I’m a medical device recruiter for Finesse Partners. My question is simple. I want to know, you’ve done a lot. What is it that you’re most proud of that you’ve done?

Dave Albert: Besides marrying my wife, actually thirty-eight years ago, smartest thing I ever did. What am I most proud of?

I’m most proud of the fact that we sell a device for $79 that is available to anyone and that kit that is used in rural India, and basically can work for in Africa, all over the world, and brings real value to people.

You know, I set off to become a doctor to help people… some altruistic notion. And when I left medicine, practice of medicine to become an entrepreneur, I did it because I thought I might be able to help more people than I could with just my hands. And I think I’ve done that, which just makes me feel pretty good.

Joseph Anderson: [Joseph Anderson] I’m the President of the Institute for Process Excellence. I think you’ve done an excellent job of telling the audience, the first level, the first big step of getting to that commercial ‘let’s go?’ What are your scars afterwards?

Joseph Anderson: Because as we all know, and many in this room might like to hear from you. How do you keep that product relevant? How do you ensure quality? How do you get the right supply chain involved because that is where my scars are from. So I think that would be great for the audience to hear.

September 2018. I get a email from a woman named Chrissy Farr, who is the health reporter for CNBC. And she says Apple is going to introduce ECG on their watch, which they did.

And I’m sitting there saying, well, my company’s dead. My chairman of the board, Vinod Khosla, calls me and says, “Best thing that ever happened to AliveCor. We’ve only grown 700% since then.

They validate your tiny voice for seven years. Personal ECG, this is important, in the world’s biggest brand, most profitable company comes into direct competition with us and says, “Hey, yeah, this is really… you got to have this.” And it just accelerated our business because oh, by the way, it’s like, we’re the experts. They’re not. I forgotten more about ECGs than they’ll ever know. And ECG technology and I can tell you that the world’s leading ECG companies all believe that so and the Cleveland Clinic and Mayo Clinic all these guys believe that and so we were able to take advantage of the market momentum that they helped create, we were there, we didn’t get killed, we didn’t get wiped out. And that, that was an insight for me. Again, the Vinod had a lot of experience, he knew that this wasn’t going to kill us, we had a good position. And that, you know, it would help us – and it has – but that doesn’t mean that we can just sit back and put our feet up. Okay, so we had to keep innovating. So we had to bring out something like my credit card ECG.

Joe Hage: Which I’d really like to, Verna, I nominate you. Please stand and approach the podium. Would you kindly, if you don’t mind, HIPAA compliance and all that stuff, would you let Dave, check out your heart rhythm?

Dave Albert: Oh, sure. Yeah, this is easy. Unfortunately, don’t have a camera. Sit down right there again, young lady.

Verna Manty Rodriguez: I think we’re the same age.

Dave Albert: Okay. That’s good. So you’re so you’re really young? Exactly. No, no, no, no, you look much younger than me.

So I’m gonna just start this up, just so she can see it. It says initializing.

So, I’m gonna hold up, because people can see, it’s actually showing her ECG in real time, see if I can just wait and get a little bigger. And so it’s recording and then it’s going to finish. It’s counting down.

Do you want me to tell you the truth? You’re good to go, girl.

Joe Hage: Can she drink tonight or no?

Dave Albert: 67 beats a minute, two, one. And then it’s gonna say boom, normal sinus rhythm.

Joe Hage: You may have a drink.

Dave Albert: So, thank you. So that device, you know, I just pulled it out of my wallet right next to the credit cards. It’s, it’s more expensive.

Verna Manty Rodriguez
: My husband has one.

Dave Albert: Oh! Your husband has one! Thanks!

By the way, my youngest graduates from college in two weeks, so just keep buying them.

Joe Hage: The next question comes from the screen. We’re just gonna play a short video and have you comment on it, please.

[Clip from “All The President’s Men” plays.] Can you share with the folks here why I would have chosen this particular video?

Dave Albert: Okay. Well, closer than me it was my dad. My dad was the Speaker of the US House of Representatives at that time. And his name was Carl Albert. He was a Rhodes Scholar from rural Oklahoma – I told you I lived in Oklahoma, down in the boonies. But he was the Speaker of the House. And he, yeah, these are some… it’s interesting because some of the people just listed their Haldeman, Ehrlichman and went to school with their sons along with a guy named Bush, a guy named Percy. A guy named Al Gore. They’re all old classmates of mine. My other classmates ever heard of Bill Gates, Steve Ballmer, Jim Cramer, Harvard Class of 77.

Joe Hage: Name-dropper!

Dave Albert: Yeah, well, you asked!

So that was that was then, you know, in in October of 1973. I was a freshman in college. And I don’t know if anybody here ever listened to Rachel Maddow’s “The Bag Man?” What happened?

Spiro Agnew, the Vice President had to resign, and my dad became first in line for the presidency. That was about five, three. And he had all these big secret service guys. It’s hilarious. Actually. I was just worried it was gonna interfere with my dating…

Joe Hage: Just, when you told the story originally about – you were asked to deplane?

Dave Albert: Oh, yeah. Okay. I was a freshman at Harvard when… and I didn’t watch any news. And I had a girlfriend in Washington DC. And you could fly from Boston to Washington, DC for $35 on what they call the student ticket.

And so, at on seven o’clock in the morning, my father called every morning… my roommates hated me! But they couldn’t say anything because my dad was important.

So that morning, got a call seven. It wasn’t my dad! It was my mom, my mom’s from Columbia, South Carolina.

And she said, “Honey, are you coming home?” And I said, Yeah, I got a date, Mom!” She said, “Well, things have changed.”

I had no idea what she was talking aboutwhich was fine. I didn’t watch the news. I had no idea the vice president resigned. So I’m on the plane landing on what is today Reagan – was the National Airport. And the captain comes on and says would “David Albert, please stay in his seat?”

Okay, so everybody gets off. And I look out and I see my dad’s limousine and I see a black SUV. And so what happened is they lowered the… this was a 727… they lowered the DB Cooper doors – remember that? In the back, 727?

And this guy comes up, this big guy. And I’m looking at him and he goes, Dave, how you doing? I’m Gil Perosko, head of your dad’s Secret Service detail. Secret Service detail? What?

Come on, we’ve got your back. And I get in my dad’s limousine and Gil gets in the front seat on his big huge backseat. I go to my dad’s driver, “What’s going on?” He says you’re going to talk to your mom.

And Gil’s just talking to me, “How’s wrestling practice?” I was a wrestler… I was a high school All-American wrestler and I was a college wrestler and went the Olympic Trials and I was like, “What is going on?!”

So get to the apartment. We walk in, this guy opens the door, there are all these people around, walk in. There’s somebody sitting in the lobby, he nods to get… on the elevator go to the top floor. We walk around the hallway and there’s a guy in a folding chair with the briefcase opened up with a cover open up towards me.

We walked by, look down. There’s an Uzi submachine gun in the in the briefcase.

We get to the door. Gil knocks on the door. Gil escorted me the whole way, “Well, we got him here.”

“Oh, thank you, Gil.”

I go in. “Mom! What’s going on?” “You don’t know.” I said no.

“The Vice President resigned and your dad’s first in line for presidency.”

I go, “Really?!”

“Yeah, they’ve got an apartment here and they’ve got a SUV. I mean, a mobile home out back and they’re on every floor,” and I went, “This is nuts! Is it going to impact my day tonight?” [Laughter.]

“No, you can drive again,” they didn’t think I was important. But that was that was crazy… happened again!

Remember? Because Richard Nixon resigned that summer in July of 1974. And once again, my dad was first in line for the presidency. His friend Gerald Ford had become the president of United States. So it was nuts. That life was nuts.

Joe Hage: I cannot remember who was Ford’s vice president.

Dave Albert: Rockefeller, Nelson Rockefeller.

Joe Hage: Okay. And how long did after he?

Dave Albert: Well, Nelson Rockefeller, later died having an event of an affair. That’s the long story. But remember, Jimmy Carter was, uh, beat Ford.

Joe Hage: I do know that but I’m wondering how long between Ford taking office…

Dave Albert: Oh, it was months.

Joe Hage: So your dad was…

Dave Albert: Oh, it was months, oh, months!

Joe Hage: Did you have, like…

Dave Albert: I didn’t have it. He did. Again, you know, today’s things are much crazier than they were then. Okay. Nobody expected that anybody would go after kids. I mean, today, I think we live in a different world. I’m not going to say a better world….

Joe Hage: He was a champion wrestler too! It’s, like, name dropping, and… he’s done it all. And he mentioned that he went to Harvard – surely, to study medicine. No, he was studying government!

Dave Albert: Well I always wanted to be a doctor. I just did that because that was the last time I was not going to study science. So I figured why not do something I’m never going to do again. And I was still pre-med. So that was a ridiculous pre-med-government-major-varsity-wrestler. That was a bad combination. That’s why I like to that’s why I wanted to go on dates.

Joe Hage: If you agree that David was an amazing keynote, would you please stand and applaud him?


Dave Albert: Thank you.