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November 29 @ 2:16 pm
Day One, October 11th: Boundary Conditions
The first day will introduce medical imaging and quantification tools used to determine vascular deformations, and to summarize current knowledge of important vascular beds including structural heart, aortic, arterial, venous, and neurovascular. These boundary conditions, which are critical for design and durability prediction, differ dramatically depending on anatomy, pathology, and implantation of devices.
Day Two, October 12th: Computational Analysis
The second day will focus on the translation of in vivo forces and displacements to the stresses and strains that ultimately determine implant durability. Finite Element Analysis will be emphasized with examples of how it can be used effectively and misused. We will also discuss future improvements in modeling techniques and verification and validation, with the end goal of using models to justify abbreviating costly clinical trials.
Day Three, October 13th: Engineering Predictions
The final day will turn to engineering mechanics and how device lifetime can be predicted from analytical stress and strains. The role of material variation will be discussed, as well as the merits of strain- based, stress-based, and energy-based approaches to fatigue. Benchtop testing, both of finished devices and “test coupons”, will be discussed in regards to shortening testing and determining safety margins.